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KMID : 0545120020120060957
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Journal of Microbiology and Biotechnology
2002 Volume.12 No. 6 p.957 ~ p.961
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Hypolipidemic Effect of Exo-Polymer Produced in Submerged Mycelial Culture of Five Different Mushrooms
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YANG, BYUNG-KEUN
PARK, JUN-BO/SONG, CHI-HYUN
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Abstract
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The hypolipidemic effect of exo-polymer produced in submerged mycelial culture of Hericium erinaceus (HE), Auricularia auricula-judae (AA), Flammulina velutipes (FV), Phellinus pini (PP), and Grifola frondosa (GF) was investigated in dietary-induced hypolipidemic rats. The animals were administered with exo-polymers at the level of 100 mg/kg body weight daily for four weeks. Hypolipidemic effect was achieved in all the experimental groups, however, HE exo-polymer proved to be the most potent one, which significantly reduced the plasma triglyceride (28.9%), total cholesterol (29.7%), low-density lipoprotein (LDL) cholesterol (39.6%), phospholipid (16.0%), and liver total cholesterol (28.9%) level, when compared to the saline administered (control) group. The results of the present investigation strongly demonstrate the potential of HE exo-polymer in combating hyperlipidemia in the experimental animals.
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